PE22.28 – Aliquot, 10mg
Data Sheet
| Application | Antagonist of the TREK-1 receptor |
| CAS | 1270083-24-3 |
| Molar Mass | 773.895 g/mol |
| Chemical Formula | C35H55N11O9 |
| Amino Acid Sequence | GVSWGLR |
| Synonyms | Spadin Analog, PE2228, TREK-1 Antagonist, PE 22 28, Sortilin Derivative, PE 2228 |
| Storage | Store at ≤4°C, tightly sealed, away from heat, light and moisture. |
| Solubility | Soluble in Water |
| Organoleptic Profile | Solid, white powder in 3mL glass aliquot |
| Composition | Each aliquot contains PE22.28 |
| Specification | PE22.28 content (per aliquot): PE22.28 10mg ±10% |
| Terms | This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Condition prior to ordering. |
Synthetic Neuropeptide for Neurotrophic and Cognitive Research
PE22.28 is a research-grade synthetic neuropeptide widely studied for its potential relevance in neurotrophic signaling, cognitive modulation pathways, neuroregenerative research, and peptide-based nootropic investigations. As an emerging investigational peptide in advanced neuroscience, PE22.28 has attracted scientific interest in models involving neuronal growth-associated signaling, synaptic plasticity pathways, and memory-related mechanisms.
Researchers have investigated PE22.28 in studies involving neurotrophic factor modulation, cognitive resilience signaling, neuroprotective pathways, and peptide-mediated neuronal repair research. Its investigational profile has made it a notable subject in advanced peptide nootropic science.
Supplied as a laboratory-grade aliquot for analytical and research applications.
Common Research Areas
- Neurotrophic Signaling Research
- Cognitive Modulation Studies
- Synaptic Plasticity Investigation
- Neuroregenerative Pathway Models
- Peptide Nootropic Research
How PE22.28 Works
PE22.28 has been studied for its potential interaction with pathways associated with neurotrophic signaling, synaptic function, and neuronal resilience. Researchers have explored its relevance in models involving growth-associated mechanisms, neuroprotective signaling, and peptide-mediated cognitive regulation.
Its neuroactive peptide profile has made PE22.28 a recurring subject in advanced neuroscience research.
Research Overview
PE22.28 has been investigated across a range of research models involving cognition, synaptic plasticity, and neuroregenerative pathways.
Areas of scientific interest include:
- Neurotrophic pathway studies
- Cognitive signaling investigations
- Synaptic plasticity research models
- Neuroprotective mechanism studies
- Peptide nootropic pathway research
Its broad research relevance continues to make it a notable compound in peptide science.
PE22.28 vs Related Compounds
PE22.28 vs Semax
PE22.28 is often researched in emerging neurotrophic peptide models, while Semax is commonly investigated as a foundational neuroregulatory peptide.
PE22.28 vs Dihexa
Dihexa has drawn interest in HGF-mimetic synaptogenesis research, whereas PE22.28 is more strongly associated with peptide-mediated neurotrophic investigations.
Frequently Asked Questions
What is PE22.28 studied for?
It is commonly researched in neurotrophic signaling, cognitive modulation, neuroregeneration, and peptide nootropic models.
What type of compound is PE22.28?
PE22.28 is classified as a synthetic neuroactive research peptide.
How should PE22.28 be stored?
Lyophilized peptide aliquots are generally stored refrigerated according to laboratory handling protocols.






