PEG-400 – Solvent
High-Viscosity Carrier Solvent for Advanced Formulation and Research Applications
Polyethylene Glycol 400 (PEG-400) is a high-purity, low-molecular-weight polymer widely used as a versatile solvent and carrier in laboratory and formulation research. Known for its excellent solubilizing capacity and higher viscosity compared to lighter solvents, PEG-400 is commonly utilized in solution preparation, compound stabilization, and extended-release delivery system investigations.
Presented in liquid form for laboratory use, PEG-400 supports a wide range of applications involving poorly water-soluble compounds and controlled formulation environments.
Common Applications
- Compound Solubilization
- Carrier for Liquid Formulations
- Extended-Release and Stability Studies
- Solvent System Development
- Analytical and Laboratory Use
Product Specifications
| Specification | Detail |
|---|---|
| Product Type | Solvent |
| Chemical Name | Polyethylene Glycol 400 |
| Abbreviation | PEG-400 |
| Form | Liquid |
| Purity | ≥99% |
| Chemical Class | Polyether Compound |
| Viscosity | Moderate to High |
| Miscibility | Miscible with water and many organic solvents |
| Storage | Store Cool, Dry, Tightly Sealed |
Key Properties
- High solubilizing capacity for a wide range of compounds
- Greater viscosity than Propylene Glycol or Ethanol
- Supports extended-release formulation research
- Low volatility and high stability
- Compatible with water, ethanol, and other solvents
Research Overview
PEG-400 is widely used in laboratory environments for preparing stable solutions, improving compound solubility, and supporting controlled delivery systems. Its viscosity and compatibility make it especially useful in formulation-focused research.
Areas of scientific use include:
- Solvent system and formulation development
- Stability and shelf-life investigations
- Controlled-release research models
- Analytical sample preparation
- Carrier system studies
PEG-400 vs Related Solvents
PEG-400 vs Propylene Glycol
PEG-400 has higher viscosity and is often used for extended-release systems, while Propylene Glycol is lighter and more suited for general solubilization.
PEG-400 vs DMSO
DMSO offers stronger solvency and membrane penetration, whereas PEG-400 provides better stability and slower-release characteristics.
Frequently Asked Questions
What is PEG-400 used for in research?
It is commonly used as a solvent and carrier for dissolving compounds, preparing formulations, and studying controlled delivery systems.
Is PEG-400 miscible with water?
Yes, it is fully miscible with water and many organic solvents.
How should PEG-400 be stored?
Store in a cool, dry place in a tightly sealed container to maintain purity and stability.






